Pharmaceutical Formulation: Suspension for Injection
Sheep/lamb, goat/kid, cattle/calf
Each vaccine dose (2 ml) consists of;
|Clostridium perfringens β toxoid||≥10 IU/ml*|
|Clostridium perfringens ε toxoid||≥5 IU/ml*|
|Cl. novyi α toxoid||≥3,5 IU/ml**|
|Cl. septicum α toxoid||≥2,5 IU/ml*|
|Cl. chauvoei master culture||≥90% protection***|
|Cl. haemolyticum master culture||≥75% protection***|
|Cl. tetani toxoid||≥2,5 IU/ml*|
|80% unit of phenol||0,0064 ml|
|37% unit of formaldehyde||0,008 ml|
* Antitoxin quantity in 1 dose-vaccinated rabbit blood sera
** Antitoxin quantity in 1 dose-vaccinated guinea pig blood sera
*** Challenge result in 1 dose-vaccinated guinea pigs
ULTRADOLL-8 is an inactive bacterin toxoid vaccine used for protection of ruminants (cattle, calves, sheep, lambs, goats and kids) against blackleg caused by Clostridium chauvoei, bacillary hemoglobinuria caused by Clostridium haemolyticum, malignant edema and bradzot caused by Clostridium septicum, gangrenous emphysema (myonecrosis) and infectious necrotic hepatitis caused by Clostridium novyi, tetanus caused by Clostridium tetani, lamb dysentery, enterotoxemia, hemorrhagic enterotoxemia, struck and pulpy kidney disease infections caused by Clostridium perfringens type B, C and D.
Annual administration of 2 ml for sheep and goats, 1 ml for lambs and kids, 4 ml for cattle and 2 ml for calves.
Animals vaccinated for the first time should be revaccinated 21 days after the first administration (Sheep and goats: 2 ml, lambs and kids: 1 ml, cattle: 4 ml, and calves: 2 ml).
From the 2nd month on, the vaccine is administered to all ages of sheep, goats, lambs and kids either by intramuscular injection or subcutaneous injection into the hairless and immobile area on axilla; and in cattle and calves by intramuscular injection or subcutaneous injection into the immobile area behind the shoulder.
|Animal Species||Injection Site||Vaccine Dose and Administration Period|
(21 Days later)
|Annual Periodic Vaccination|
|Sheep/Goats||Intramuscular injection or Subcutaneous injection into the hairless and immobile area on axilla||2 ml||2 ml||2 ml|
|Lambs/Kids||Intramuscular injection or Subcutaneous injection into the hairless and immobile area on axilla||1 ml||1 ml||1 ml|
|Cattle||Intramuscular injection or Subcutaneous injection into the immobile area behind the shoulder||4 ml||4 ml||4 ml|
|Calves||Intramuscular injection or Subcutaneous injection into the immobile area behind the shoulder||2 ml||2 ml||2 ml|
Stored at + 2/8ºC, and in the dark. Shelf life is 2 years. Do not freeze
The vaccine is packaged in 20, 50, and 100 ml amber colored type II glass bottles or 20, 50, 100, 200, 250 and 500 ml plastic bottles containing 10, 25, 50, 100, 125 and 250 sheep, goat and calf doses; 5, 12, 25, 50, 62 and 125 cattle doses; and 20, 50, 100, 200, 250 and 500 lamb and kid doses. Not all forms of packaging may be placed on the market. Each bottle with a butyl stopper and an aluminium cap is placed on the market as boxed in 50 or 100-unit styrofoam viols which contain the same number of leaflets.